Family Guy Season 16 Family Guy's sixteenth season premiered on Fox in the United States on October 1, 2017. The series follows the dysfunctional Griffin family, consisting of father Peter, mother Lois, daughter Meg, son Chris, baby Stewie and the family dog Brian, who reside in their hometown of Quahog. The executive producers for the sixteenth production season are Seth MacFarlane, Richard Appel, Alec Sulkin, Steve Callaghan, Danny Smith and Kara Vallow. Sulkin returns after a two-season absence as the new showrunner for the series, replacing previous showrunner Callaghan. Appel will continue to serve as showrunner alongside Sulkin. The season will feature guest appearances from Danny Trejo, Ian McKellen, Kristen Bell, Louis C.K., Ty Burrell, Julie Bowen, Sofía Vergara and Bill Maher. The season will also mark the final appearances of Adam West and Carrie Fisher, as well the show's 300th episode.